Medicines
Prosonix is the world leader in use of ultrasonic pharmaceutical particle engineering technologies for the manufacture of high value pharmaceutical powders and Making Better Medicines. Our pipeline addresses the fast-growing market sectors of asthma, COPD and other respiratory disorders, as well as niche opportunities in orally and parentally delivered products. Prosonix proprietary technologies can be used for API manufacture at any scale.
Particles
Prosonitron™, DISCUS®, UMAX®, SAX™ and PRT based process technologies are proprietary “Solution-to-Particle” methods for controlling crystal size, shape and polymorph for APIs, aimed at Making Better Medicines. Technologies offer dose-to-dose uniformity, formulation consistency, stability and 200% performance increase of inhaled APIs compared to micronized. Combination particles of multiple APIs can be manufactured.
Ultrasound
Power ultrasound facilitates controlled and reproducible crystal nucleation which is fundamental in controlling crystallization. Sonocrystallization delivers controlled nucleation and superior control of particle size, morphology, polymorphism, crystallinity and purity, and in doing so helps eliminate the need for troublesome external seeding and micronization for inhaled medicines.
SonoLab
Multipurpose laboratory equipment for sonocrystallization & sonochemistry are now available. These highly effective and flexible research tools facilitate 100ml – 100L operational capability in batch or continuous operation and can be integrated with automated laboratory reactors. The unique designs allow seamless transition and scale up to Prosonitron™ technology for commercial scale operation.
Prosonitron
Prosonix provide cGMP & ATEX sonocrystallization Prosonitron™ ultrasonic process and reactor technology. They are aligned with emergent FDA “QbD” and “Design for Intent” philosophy. Our proprietary systems are of modular design for optimum flexibility and are an easy retro-fit to existing equipment. They are proven across scale in API production and can be seen as sustainable green technology.
| November 3-4, 2010: Crystallization & Polymorphism, Florida |
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| Written by Graham Ruecroft |
| Sunday, 04 April 2010 00:00 |
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http://www.scientificupdate.co.uk/              |
| Last Updated on Thursday, 15 April 2010 16:17 |
Prosonix CTO Dr Graham Ruecroft will be presenting and chairing a seesion at the 9th International Conference and Exhibition on Polymorphism & Crystallization organised by Scientific Update, UK, taking place 3-4 November 2010 at Sheraton Sand Key Resort, Clearwater Beach, Florida. He will talk about Particle Engineering of Inhalable Medicines Using Spray Drying and Ultrasound Mediated Amorphous to Crystalline Transition (UMAX). The conference will feature the chemical development issues of solid-state chemistry and in particular will focus on the reproducible production of organic crystals in the correct form (habit, solvate, polymorph) and particle size. For further details please refer to:
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Newsflash
| Prosonix is pleased to announce the launch of its UMAX® technology - an acronym for Ultrasound Mediated Amorphous to Crystalline transition - which is a new disruptive particle engineering technology set to revolutionise respiratory medicine. The proprietary technology has now been demonstrated on over 30 generic and novel drug molecules and combination products. |
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