1. Large scale co-crystal approaches
(Blog/blog)

... can be excellent - see patents on sonic slurry by Scott Childs. We are finding we get fantastic results for co-crystal preparation by avoiding API + co-crystal former slurries and using ultrasonic cavitation ...

2. November 3-4, 2010: Crystallization & Polymorphism, Florida
(events/events)

... place 3-4 November 2010 at Sheraton Sand Key Resort, Clearwater Beach, Florida. He will talk about Particle Engineering of Inhalable Medicines Using Spray Drying and Ultrasound Mediated Amorphous to Crystalline ...

3. Prosonix CEO David Hipkiss talks to CHEManager
(News/Latest)

David Hipkiss, CEO of Prosonix, recently spoke to CHEM-anager Europe about the company's endeavours in using its proprietary sonocrystallization and particle engineering technologies for Making Better ...

4. KTP Research Funding For Prosonix and Bath University
(News/Latest)

... aim of this KTP project is to explore current laboratory scale techniques and eventually design and develop robust industrial process methodology using proprietary equipment. This will eventually lead ...

5. SonoLab
(technology/Technology)

... leading to batch to batch consistency - Optimised crystallization experiments carried out at laboratory scale can be scaled to pilot plant processes and manufacturing using the ProsonitronTM range of ...

6. FDA Quality by Design
(Pharmaceuticals/Pharmaceuticals)

... (the ICH Q8 guidelines of 2004) the pharmaceutical industry to improved invention, development and commercialization of structured products using technologies that will result in superior product quality. ...

7. Ultrasonic Particle Rounding
(technology/Technology)

... dry milling or micronization. In addition the judicious application of ultrasound using a Prosonitron configured in a recirculation loop with existing batch crystallizer as shown can lead to remarkable ...

8. DISCUS: Dispersive Crystallization with Ultrasound for Manufacture of Mesoscopic Particles
(technology/Technology)

... Molecule-to-Particle techniques using power ultrasound such as anti-solvent precipitation take advantage of the excellent dispersive and crystal nucleation properties of transient cavitation. The precipitation ...

9. Combination Therapy
(Pharmaceuticals/Pharmaceuticals)

... of 2 or more micronized powders. Thus multiple APIs in the correct dose ratio can be symbiotically crystallized in a single perfect particle. We have assessed the in vitro delivery (using Next Generation ...

10. Inhalation
(Pharmaceuticals/Pharmaceuticals)

... we can develop more useful drug formulations.     Budesonide We have carried out rigorous in vitro inhalation studies using external partners on Prosonix engineered Budesonide, and inhaled corticosteroid ...

11. Sonocrystallization
(technology/Technology)

... technology can be used in in-line continuous flow mode, or batch mode for in-situ generation of seed crystals using the process liquid itself as the source for the seeds, thus overcoming one of the major ...

12. Prosonitron Technology
(Engineering/Engineering)

... as shown left. Using this method of scale-up, the processing environment, always based around transducers bonded to a 6" pipe, can be maintained.   Two standard materials of construction for the walls ...

13. Pharmaceutical Manufacture
(Pharmaceuticals/Pharmaceuticals)

... products using technologies that will result in superior product quality. Due to the limitations of conventional crystallization techniques macroscopic particles for say tablets (10-200 micron) and ...

14. Capabilities
(About us/about us)

... delivery with the prime objetive of manufacturing better medicines. Collaborative Research and Process Development Using Prosonix proprietary technologies and expertise our dedicated team of chemists ...

15. Minerals
(Markets/Markets)

... in our Press Releases. Alumina is principally manufactured using the common Bayer process and is employed at over 50 alumina refineries worldwide, with total production exceeding 60 million tonnes ...

16. Intellectual Property
(technology/Technology)

... D.; WO 2010/007447 Entrainment in anti-solvent: Ruecroft, G.; Robinson, J.; WO 2008/114052 Crystalline particles using immiscible anti-solvent:solvent: Ruecroft, G.; Robinson, J.; Parikh, ...

17. Equipment
(technology/Technology)

... chemicals and pharmaceuticals to bulk inorganics, harnessing the power of acoustic cavitation. Hitherto the phenomenon of using ultrasound to influence nucleation had been used to build a strong ...

18. CrystalGEM Predictive and Highly Focussed Crystallization Screening
(technology/Technology)

... polymorphs, solvates and single crystals for X-ray diffraction studies, and all for using less than 200 mg of your valuable pharmaceutical ingredient. CrystalGEM can be applied to pharmaceutical crystallization ...

19. New SonoLab Development Suite Launched
(News/Latest)

... it is small batches, continuous or continuous with recirculation, this equipment has the flexibility to deliver batches of up to 2 litres. SonoLab™ Development - Using a larger reactor, this moves development ...

20. Prosonix and Aeropharm Announce Agreement
(News/Latest)

... Using Prosonix's sonocrystallization technology can eliminate the need for milling and micronization by enabling the construction and isolation of ideal crystalline particles directly from solution. The ...