1. Large scale co-crystal approaches
(Blog/blog)

... can be excellent - see patents on sonic slurry by Scott Childs. We are finding we get fantastic results for co-crystal preparation by avoiding API + co-crystal former slurries and using ultrasonic cavitation ...

2. UMAX Pharmaceutical Particle Engineering
(technology/Technology)

... API powder of the correct particle size distribution. 2. Ultrasonic processing of the API loaded into a non-solvent liquid to form a slurry. 3. Final isolation (either by spray drying or supercritical ...

3. Prosonix CEO David Hipkiss talks to CHEManager
(News/Latest)

... Medicines. Within this discussion David spoke at length about the application of proprietary pharmaceutical ultrasonic particle engineering technologies, ultrasonic process chemistry and processing equipment ...

4. Prosonix Attains International Quality Approval
(News/Latest)

... external auditors SGS (UK) Ltd.   This covers Prosonix full range of activities from the Research and Development of ultrasonic particle engineering solutions for crystallisation and formulation ...

5. Prosonitron
(slider/slider)

Prosonix provide cGMP & ATEX sonocrystallization Prosonitron™ ultrasonic process and reactor technology. They are aligned with emergent FDA “QbD” and “Design for Intent” philosophy. Our proprietary systems ...

6. Medicines
(slider/slider)

Prosonix is the world leader in use of ultrasonic pharmaceutical particle engineering technologies for the manufacture of high value pharmaceutical powders and ultimately Making Better Medicines. Our pipeline ...

7. SonoLab
(technology/Technology)

... vessels with the addition of the Prosonix proprietary ultrasonic flow cell, generator and pump. The powerful Atlas Software allows full control of all the important parameters required for sonocrystallization, ...

8. Ultrasonic Particle Rounding
(technology/Technology)

Ultrasonic Particle Rounding Technology (PRT) is exclusively in-licensed to Prosonix (US 6669122). Used in combination, this process technology and the proven Prosonix ProsonitronTM process and reactor ...

9. DISCUS: Dispersive Crystallization with Ultrasound for Manufacture of Mesoscopic Particles
(technology/Technology)

... conditions must be chosen to maximise crystal nucleation at the expense of growth.   We can take advantage of these effects by mixing in the presence of an ultrasonic field. The two streams can be ...

10. Prosonitron Technology
(Engineering/Engineering)

... independent power setting.        Ultrasonic power to be delivered to each row of transducers can be set by the user and electronic controls built into the system will automatically adjust electrical ...

11. Scale-up
(Engineering/Engineering)

... HD or P750 HD can be achieved with confidence as the geometry and intensity of the ultrasonic environment is maintained during the scale-up process. Throughput capabilities of a single P500 HD would be ...

12. Engineering
(Engineering/Engineering)

Ultrasonic Processing | Prosonitron Technology | Scale-up Also see: Equipment for further information about the diversity of of ultrasonic processing equipment. Prosonix technologies are underpinned ...

13. Pharmaceutical Clients
(Pharmaceuticals/Pharmaceuticals)

... refer to the attachments. Aeropharm Prosonix have entered into a new agreement with Aeropharm (Rudolstadt, Germany) for application of its proprietary ultrasonic particle engineering technology for ...

14. Ultrasonic Processing
(Engineering/Engineering)

... and suddenly collapses in an event that generates an intense release of energy. These localised cavitation events are the main work horse of mechanical ultrasonic processing and can be used to stimulate ...

15. Scientific Advisors
(About us/about us)

... involving process chemistry, crystallisation and polymorphism and related issues. In 2003, he was appointed visiting professor at Sussex University Ultrasonic Process Technology and Science - Professor ...

16. Technology
(technology/Technology)

Equipment | References | SAX | CrystalGEM | Sonocrystallization | DISCUS | Ultrasonic Particle Rounding Controlling and actively manipulating nucleation and subsequent crystal growth behaviour is fundamental ...

17. Capabilities
(About us/about us)

... enhance their own ultrasonic capability and optimize  current solid-state primary and secondary manufacturing processes. Proof of Concept / Proof of Process studies This is the initial stage of evaluation ...

18. Equipment
(technology/Technology)

... and do not transmit the ultrasonic energy uniformly, leading to non-standard nucleation. Further, transmission of the ultrasonic field to bulk volumes is precluded as the acoustic field emanating from ...

19. Prosonix and Aeropharm Announce Agreement
(News/Latest)

Prosonix Ltd (Oxford, UK) is delighted to announce a new agreement for the application of its proprietary ultrasonic particle engineering technology in the pharmaceutical industry. This new agreement has ...

20. How we can work together
(About us/about us)

... replicate the process at representative scale. The cost of the pilot trial is based on the rental cost of the ultrasonic reactor over an agreed time period, plus technical support as required. In addition, ...