1. Large scale co-crystal approaches
(Blog/blog)

... batch continuous - just think spray-drying. The key is to have efficient use of 20-40 kHz ultrasound, and importantly have the ability to scale-up to commercial production with viable industrial sonocrystallization ...

2. Scale-up of co-crystals
(Blog/blog)

There appears to be a number of people looking into ways to up-scale co-crystals (from the bench) by conventional batch crystallisation. Having had discussions on continuous crystallisation as an alternative ...

3. Prosonix Announce The Scale-Up Of UMAX technology
(News/Latest)

In just a short space of time since its launch Prosonix has successfully scaled up of the UMAX® particle engineering technology. The scale-up has now been carried out on several APIs in cGMP facilities ...

4. Prosonix Announce The Scale-Up Of UMAX technology
(News/Newsflash)

In just a short space of time since its launch Prosonix has successfully scaled up of the UMAX® particle engineering technology. The scale-up has now been carried out on several APIs in cGMP facilities ...

5. Prosonix Announce The Launch Of UMAX technology
(News/Latest)

... full scale cGMP in 2010. Importantly UMAX® does not utilise destructive high energy milling classically used in the preparation of inhalation medicines.  This historic methodology introduces significant ...

6. Prosonix Announce The Launch Of UMAX technology
(News/Newsflash)

... full scale cGMP in 2010. Importantly UMAX® does not utilise destructive high energy milling classically used in the preparation of inhalation medicines.  This historic methodology introduces significant ...

7. Prosonitron
(slider/slider)

... are of modular design for optimum flexibility and are an easy retro-fit to existing equipment. They are proven across scale in API production and can be seen as sustainable green technology.  ...

8. SonoLab
(slider/slider)

... continuous operation and can be integrated with automated laboratory reactors. The unique designs allow seamless transition and scale up to Prosonitron™ technology for commercial scale operation.  ...

9. Medicines
(slider/slider)

... can be used to manufacture Active Pharmaceutical Ingredients at any scale.  ...

10. KTP Research Funding For Prosonix and Bath University
(News/Latest)

... aim of this KTP project is to explore current laboratory scale techniques and eventually design and develop robust industrial process methodology using proprietary equipment. This will eventually lead ...

11. Prosonix and Syrris launch SonoLab
(News/Latest)

... scale sonocrystallization and sonoprocessing equipment, the two companies are pleased to announce the launch of the proprietary  ...

12. SonoLab
(technology/Technology)

... leading to batch to batch consistency - Optimised crystallization experiments carried out at laboratory scale can be scaled to pilot plant processes and manufacturing using the ProsonitronTM range of ...

13. Meet Prosonix at Informex 2009
(News/Latest)

... applications development and more. Prosonix technologies are proven across scale to give quantifiable productivity and performance enhancements in the primary and secondary manufacture of API's, excipients ...

14. Ultrasonic Particle Rounding
(technology/Technology)

...      Oxcarbazepine (image left)- scale-up using Prosonitron leads to well defined rounded particles starting from more rod-like crystals. Diltiazem HCl; an hypertension API – PRT ...

15. DISCUS: Dispersive Crystallization with Ultrasound for Manufacture of Mesoscopic Particles
(technology/Technology)

... produced a number of microcrystalline steroids by this ‘reverse’ process and see this as an effective means of preparing mesoscopic crystalline particles at truly industrial scale. The options are quite ...

16. Sonocrystallization
(technology/Technology)

... add significant value-added benefits and are capitalised through new process patents that can be created for individual products, thus securing and extending marketing timescales. Sonocrystallization can ...

17. Prosonitron Technology
(Engineering/Engineering)

... as shown left. Using this method of scale-up, the processing environment, always based around transducers bonded to a 6" pipe, can be maintained.   Two standard materials of construction for the walls ...

18. Scale-up
(Engineering/Engineering)

... energy input that should be applied continuously. Typical requirements for these processes lie in the region of 10 kJ/litre to 100 kJ/L.     For pre-pilot laboratory scale development the Sonolab ...

19. Engineering
(Engineering/Engineering)

Ultrasonic Processing | Prosonitron Technology | Scale-up Also see: Equipment for further information about the diversity of of ultrasonic processing equipment. Prosonix technologies are underpinned ...

20. Scientific Advisors
(About us/about us)

... Manufacturing and Scale-up Consultancy (Scientific Update) - Dr Trevor Laird http://www.scientificupdate.co.uk Trevor Laird is an international consultant and expert witness. He has many years experience ...